Becker Muscular Dystrophy Medical Genetics Health And Social Care Essay

Muscular dystrophy is a familial upset that bit by bit weakens the organic structure ‘s musculuss. It is caused by incorrect or losing familial information that prevents the organic structure from doing the proteins needed to keep healthy musculuss. There are different types of muscular dystrophies that consequence different musculuss and consequences in different grades of musculus failing. But specifically two types are of import: Duchenne muscular dystrophy Becker muscular dystrophy. Duchenne muscular dystrophy: Duchenne muscular dystrophy ( DMD ) is a terrible recessionary X-linked signifier of muscular dystrophy characterized by rapid patterned advance of musculus devolution. It is normally seen in males ( 1 in 3500 ) . Females are largely bearers, specifically do non demo any symptoms. The upset is caused by mutant in DMD cistron, located in human chromosome Xp21. DMD may ensue from m-RNA that contain out-of-frame displacement ( omissions, interpolations or splicing site mutants ) .This cistron codifications for Dystrophin protein, an of import structural constituent of musculus tissue. Dystrophin is responsible for linking the cytoskeleton of each musculus fibres to the underlying basal lamina through a protein complex incorporating many fractional monetary units. Symptom: The chief symptom of DMD is a progressive neuromuscular upset, is muscle failing associated with musculus blowing with the voluntary musculuss being affected, particularly pelvic and calf musculuss. Awkward mode of walking, running or stepping Frequent falls Fatigue Skeletal malformations ( scoliosis ) Increased lumbar hollow-back, taking to shortening of hip-flexor musculuss Pseudohypertophy of the calf musculuss Cardiacmyopathy is common Grower ‘s mark is seen in people who has terrible damage of lower appendages. DUCHENNE MUSCULAR DYSTROPHY ( DMD ) is a familial disease in which the musculus of a patient ( male child ) suffers progressive harm, due to miss of dystrophin protein. It is a long unwellness in which the musculuss of a patient become bit by bit weaker and it later effects indispensable mechanism ( respiratory system, nervous system, bosom etc ) of the organic structure taking finally to decease of the DMD patient during early Twentiess ( 15 + year. )Diagnosis:Deoxyribonucleic acid trials Prenatal trials Muscle biopsy Deoxyribonucleic acid trials: The musculus -specific isoform of the dystrophin cistron is composed of 79exons, and DNA testing and analysis can normally place the specific type of mutant of the coding DNAs that are affected.DNA trial confirms the diagnosing in most instances. Prenatal trials: If one or both parents are bearers so there is a opportunity of inheriting to the following coevals, for this there are some antenatal trials. At 11-14 hebdomads of gestation chorionic villous sampling, at 15 hebdomads amniocentesis, at 18 hebdomads foetal blood sampling is done. Muscle biopsy: A little sample of musculus tissue is taken with a scalpel and a dye is applied that reveals the presence of dystrophin. Creatine kinase ( CPK-MM ) degrees will be high in blood watercourse. Familial testing can uncover familial mistakes in Xp21 cistron.Treatment:Corticosteroids such as Pediapred and deflazacort addition strength and energy of musculuss. Beta -2 agonists besides increase musculus strength Physical therapy is helpful to keep strength, flexibleness, and map Orthpaedic contraptions ( such as braces and wheelchairs ) may better mobility and self-care Stem cell replacing. Case survey: An 18-month-old male child was referred for neuromuscular rating and intervention following a visit with the household ‘s community baby doctor. Earlier lab work had revealed a Creatine Kinase ( CK ) degree of over 15,000 – consistent with neuromuscular disease. The male child ‘s female parent reported a household history of Duchenne Muscular Dystrophy ( DMD ) on her side. She has older kids, including another male child who is unaffected. Evaluation by a brain doctor, including a musculus biopsy, indicated the presence of DMD. The male child was referred to a paediatric rehabilitation medical specialty doctor for farther rating. Physical scrutiny showed the kid ‘s musculus tone was decreased, and he had pseudohypertrophy ( enlargement ) of his calf musculuss. He had full scope of gesture in his weaponries and legs, and was walking by himself. His female parent reported that he began walking at about 14 months of age. Although he moved reasonably good from sitting to standing, he did utilize a modified Gowers manoeuvre ( forcing up with his custodies on his articulatio genuss and legs, with his underside up, to accomplish a standing place ) . This is typical with Duchenne dystrophinopathy, bespeaking lower appendage failing around the hips and articulatio genuss. Neck musculus and upper appendage strength was satisfactory. The kid ‘s cognitive map appeared to be normal, and he was synergistic. His female parent reported that he participates good in age-appropriate activities with his equals. However, she did notice that he tired more easy than other kids his age. These findings are characteristic for DMD at an early age. The doctors discussed the kid ‘s hereafter with his parents, including possible intervention options as his disease progresses. Those options include assistive devices ( such as braces and mobility devices ) , physical and occupational therapy appraisals and intervention, and drug therapy. A familial counsellor interviewed the household and arranged for molecular familial testing to see if the kid has a cistron omission associated with DMD. Familial testing can assist nail the exact nature of DMD, every bit good as aid place if other household members could be affected. Referrals were besides made to societal services, to assist both the kid and his household place their strengths and demands within their community. As portion of the intervention program, the doctors recommended that the kid return to the neuromuscular clinic every six to twelve months for re-evaluation and necessary intercessions as he grows and develops. Timely intercessions, to assist forestall or decelerate complications related to DMD, will assist the kid maintain the best possible quality of life and might increase length of service. The male child was scheduled to undergo baseline testing of his strength, scope of gesture and functional ability by one of the healers the following clip he returns to clinic. Baseline proving can assist set up current map, every bit good as quantify the demand for and effectivity of specific interventions. Future baseline testing by cardiology and pulmonology services can besides assist the determination devising procedure.BECKER MUSCULAR DYSTROPHY:Becker muscular dystrophy is similar to Duchenne muscular dystrophy, but is less common and progresses more easy. This affects about 1 in 30,000 male childs than in females. This is a familial X-linked disease characterized by the change of the distrophin cistron merchandise, a structural protein of import for keeping unity of skeletal and cardiac musculus cell cytoskeleton. Changes are normally due to inframe omissions or point mutants of the distrophin cistron, which is located on the chromosome Xp211. The skeletal musculus in this patient besides showed about all of the histological characteristics of Becker muscular dystrophy, including mortification, regeneration, endomysial fibrosis, dividing fibres and unnatural fluctuation in fiber size. Cardiac failure is the most common cause of decease in Becker muscular dystrophy patients. It is postulated that impaired myocardium leads to an increased work load on the left ventricle, leads to go forth ventricular expansion and mitral valve distension. This patient had terrible myocardiopathy with left and right ventricular expansion and mitral and tricuspid valve distension. Pulmonary vascular thickener suggests the presence of left bosom failure with subsequent development of pneumonic high blood pressure taking to right ventricular distension and possible right bosom failure.Symptoms:Many childs with muscular dystrophy can follow normal form of development during first few old ages of life. But in clip the symptoms began to look. A kid with MD may get down to falter, toddle, hold trouble in traveling upstairs, and a toe walk. A kid may get down to fight to acquire up from sitting place or hold difficult clip in forcing things like waggon. Childs with MD develops enlarged calf musculus ( pseudohypertrophy ) as musculus tissue is replaced by fat. Frequent falls Trouble in running, hopping, leaping Loss of musculus mass Breathing jobs Congestive bosom failure Loss of balance and coordination, wearinessTrials:CPK blood trial Electromyography ( EMG ) nervus proving Muscle biopsy or familial blood trial Diagnosis: The trials to find what type of MD is involved and to govern out other diseases that could do the job. These might include a blood trial to step degrees of serum creatine kinase, an enzyme that ‘s released into the blood stream, when musculus fibres are deteriorating. Elevated degrees indicate that something is doing musculus harm. The physician besides may make a blood trial to look into the Deoxyribonucleic acid for cistron abnormalcies or a musculus biopsy to look for forms of impairment and unnatural degrees of dystrophin, a protein that helps muscle cells maintain their form and length. There are several major signifiers of muscular dystrophy, which can impact the musculuss to changing grades. In some instances, MD starts doing musculus jobs in babyhood ; in others, symptoms do n't look until maturity. There is no remedy for MD. Doctors are working on bettering musculus and joint map and decelerating musculus impairment so that those with MD can populate as actively and independently as possible. Treatment: There is no known remedy for Becker muscular dystrophy. The end of intervention is to command symptoms to maximise the life of the affected individual. Doctors prescribe steroids to assist maintain a patient walking for every bit long as possible. Activity is encouraged. Inactivity ( such as bed remainder ) can do the musculus disease worse. Physical therapy may be helpful to keep musculus strength. Orthopedic contraptions such as braces and wheelchairs may better mobility and self-care. Familial guidance may be recommended. Daughters of a adult male with Becker muscular dystrophy may transport the faulty cistron and could go through it onto their boies.Examples:( dual heterozygote ) : Becker muscular dystrophy and X-linked colour sightlessness Jonathan, a 10-year-old male child, has Becker muscular dystrophy and colour sightlessness. His female parent, Mary, has normal colour vision, but her two brothers and maternal uncle have red-green colour sightlessness. Based on her household history, Mary is an obligate heterozygote, or bearer, of the X-linked cistron mutant for colour sightlessness. Molecular proving confirms that she besides carries a omission in one of her X-linked DMD cistrons, which accounts for the Becker muscular dystrophy in her boy. Though the two conditions are unrelated, Mary is known to be heterozygous at two separate venues on the X chromosome and is hence a dual heterozygote.Case survey:A 28 twelvemonth old adult male was admitted for haemoptysis, dyspnoea, febrility, icinesss, sickness, emesis, and icterus. At age 12 old ages, he was noted to hold scoliosis, and he described trouble running. Additional clinical findings at the clip of his first rating were enlarged calf musculuss, atrophic thoracic mu sculuss, elevated creatine phosphokinase degrees, every bit good as an unnatural EMG and musculus microscopy. The patient was was non followed for his status between the ages of 12 and 24 old ages. At the age of 24 old ages, echocardiography showed a badly dilated left ventricle with terrible planetary hypokinesis, mild atrial expansion, possible mural apical thrombus, and a little pericardiac gush. The patient was placed on Vasotec and Lanoxin. Repeat echocardiogram at the age of 27 old ages showed similar findings, and the patient was placed on Coumadin anticoagulation to forestall cardiac mural thrombi and emboli. Four months prior to his concluding admittance, he was hospitalized briefly for pneumonia and left ventricular bosom failure with pneumonic congestion. Given his deteriorating cardiac position, the patient was later placed on the cardiac organ transplant list two hebdomads prior to admittance. Past medical history revealed that his younger brother was diagnosed at age 14 old ages with dilated myocardiopathy that resulted in decease three hebdomads following the oncoming of terrible acute congestive bosom failure. Two other siblings and his parents are free of bosom disease. When admitted, the patient had haemoptysis, dyspnoea, febrility, icinesss, sickness, emesis, and icterus. His international normalized ratio on admittance was 6.6, and his white blood cell count was 16,400/uL. A chest X ray showed a mass-like consolidation of the right lower lobe of lung. He continued to hold episodes of haemoptysis, elevated white blood cell counts and elevated international normalized ratios asking Vitamin K therapy. Five yearss after admittance, the patient noted chest firing following bronchioloalveolar lavage. Shortly thenceforth, he was found to be asystolic without respirations. Cardiopulmonary resuscitation failed, and the patient died. The necropsy was limited to the thorax.

The Indian History Essay Paper

OB Notes Paper Pattern: 100 Marks: Q1. Compulsory. Based on â€Å"Ek ruka hua faisla† (Answer any 4 out of 7 options). Example question: Personality & Leadership Traits of Character No. 7 in the movie†¦ Q2 – Q7. Answer any 4 (20 marks each) Q2. would be Short Notes Q3. – Q7. – Each question would be of two parts (A&B). Part A – Theory & Part B – Caselets in DPA format Tip: Please answer in Bullet points only. Topics: 1. Basic of Behaviour 2. Organisation – context of opp and Interdependence 3. Personality 4. Beliefs & Paradigms 5. Groups & Teams – Composition, Advantages, Disadvantages, formal, informal, How best teams come into existence. . Core Values & Adaptive Values 7. Five levels of change 8. Adaptation & Leadership Theory 9. Learning 10. Conflict 11. Basic of Motivation – stress management & Time management, Traits from 6 Personality Traits for Transformational & Transactional, Motivation & Morale Theories: 1. Blate & Motoun Managerail Grid. 2. Ringlemen Effect 3. Bruce & Tactman Model of Team formation 4. Malow’s Pyramid 5. The Medici Effect – franz Johamsson 6. The fifith Discipline – Peter Senge 7. Classic Conditional Theory of Learning 8. Stimulus Response Learning 9. REBT – Rational Emotive Behaviour Theory 10. The Ice berg model 1. The Big 5 model 12. Cattell’s 16 Personality Factor 13. Thomas Profiling 14. FIROB 15. MBTI 16. Johari Windows 17. Transactional Analysis 18. DISC # Genesis of OB: -Psycology -Sociology -Social Psycology -Anthropology -Political Science †¢Behaviour is an Action †¢Communication leads to behaviour †¢We communicate at all times †¢Types of Communication -Verbal -Non-Verbal -Written # Unsound Behaviour & Sound Behaviour # Sound Behaviour is Type B Behaviour -Communication is Basic -You communicate all the time -â€Å"B† is a form of communication, it is external. -Value at bottom â€Å"B† is adapted value Core values are common to all of us # Value: (Ringleman Effect) – Core Values & Adapted Values: Sound Behaviour is outcome of sound values – Value is a 3 leg Tool: Comfort Zone, Meaningfullness, Identity #Structural Conflicts of Values: Value Level Person APerson B HighHonesty Money ————– ————– – ————- LowMoneyHonesty -Nature of Human is â€Å"Dynamic†, not static -Self Deception # How to resolve conflict in such situation? Approach – Diagnosis, Prescription & Action 1. Individual Discussion (with person A & person B separately) 2. Value check of each individual 3. Identify individual goals . Common Goal (Creation of super ordinate goals so that values of both the person are not diluted) Topic 2: Team & Group #Team: -Team is like entity -It does not form by itself. It is created outside -Taken as human being, it has its own value -Team i s considered as organic body & has emotion & cohesiveness -Team has to be flexible to achieve the super-ordinate goals (common goal/combined goal of different persons) -Team is only when it is comprised of experts -Every member of team has to be an expert in a particular field -Success or failure of the team is because of the leader †¢Stages in Formal to Informal: 1.Forming: Introduction, bringing team together, bringing about unification 2. Storming: Conflict management & leadership, ego clashing, most important parts are resolved, it is always never ending. 3. Norming: Settle down. 4. Performing †¢Steps a Leader has to take: 1. Cohesiveness 2. Team building (strengthening the team together towards an activity) 3. Differences have to be brought down to convergence of difference 4. develop dependence between team members to have convergence of difference # Group: -It is collection of resources (money, men, material, machine) – denominated by man power -Can be formed externally or internallyFormal GroupsInformal Groups 1. Goal forms outside1. Stated bonding 2. It is governed by certain rules2. Discipline is lacking 3. Restricted3. Impenetrable 4. Goal oriented4. They make or break the organisation 5. Communication & bonding not very strong5. Communication and bonding is very strong 6. Conditional behaviour towards goal achievement 7. Values may or may not exist6. Values do exist 8. Motivation driven by goal # Merits of Formal Groups: -Structured -Rule oriented -Disciplined -Goal oriented -Goal focused -KRAs, Duties are very clear -Stakes are very high, hence behaviour based on stakes # Demerits of Formal Groups: Restricted Behaviour -No transparency, not genuine -No natural bonding -No values & conflicts are always hidden # Informal Groups: -Within every formal structures group, we always have informal groups -In an organization each one is at a level & has got: i. Power ii. Authority iii. Accountability iv. Responsibilities -Energy of informal groups should be used towards productivity -They can make or break an organization -They would not allow or permit a member from another informal group with value or value system different from his group as the values and the comfort zones & identities are different. 2 Laws of Communication: 1. Law of Entertainment: When 2 bodies are in proximate they eventually entertain – get affected by each other. 2. Law of Synchronicity: When 2 bodies entertain over a period of time they eventually synchronize – characteristics of one tends to rub of into the other & viz (emotional exchange). â€Å"Reprimand in private and praise in public† # 4 Zones in Life: 1. Internal Zone: Where you operate from your home. It is suppose to have nurturing, advice, criticism, corrections. 2. Spiritual Zone: Individual Commitment with spirit 3. Work Zone: 4.Social: Outside the work place & home. All the people you meet outside the work & home. # Organisation Structure # HR Audit # Upward Spiral # Learning Curve # Attitude: -Congruent (Behaviour in line with thoughts) -Dissonant (difference in behaviour and thoughts) # Stagnation Stage # Learning: Knowledge + Actions (repeated actions) = Skills â€Å"A learning is a learning when certain body of knowledge is effectively transferred into actionable skills† -Skill development: Intensifying existing & enhancing new skills -Phase of Learning of an employee in an organization: 1st Phase: Technical Skills nd Phase: Behavorial Skills 3rd Phase: Conceptual Skills -Two types of Learning: a)Active: Self-driven desire to learn. When an individual experiences the need to change, the learning becomes active. b)Passive: Forced by situations & circumstances -It is upto the individual driven by his values & perceptions to choose to actively learn or reject the learning till it reaches its higher stake -When an individual a change about to happen in future & that to with meaningfulness, he/she is on critical path of learning - Awareness of change normally initiates active learning Learning is the courage of acquiring knowledge & putting into action -Learning has ethical & moral needs # Why do we learn? -Need to Change -Situations -High Stakes # Learning Block -Unawareness -Attitude (Is the knowledge really required by me?†¦. ) # Change # Types of Change: -Percieved & Non- Percieved -Fast Change & Slow Change †¢Those changes which are perceivable by our sensory experiences are perceivable changes, whereas those which do not fall under perceivable changes are termed as non-percievable changes. # 5 Levels of Change: 1. Cosmic Change (Changes in Galaxy) 2. Environmental (Global Warming) . Social Changes (Society) 4. Organic Changes (Body) 5. Cellular †¢The whole universe is in the process of eternal change. Change is required for evolution. †¢The purpose of change is to adapt & evolve †¢Adaption mean acceptance of change by addressing values & perception & thereby behaviour †¢Adj ustment is painful, adaption is powerful †¢Adaption occurs when an individual develops self awareness of change, continuously learns & develop lateral skill # 4 Stages of Learning: 1. Unaware of incompetency (Ignorance) 2. Aware of the incompetancy (Knowledge) – Stage where you stay or quit 3.Aware of competency (Skills) 4. Unaware of competency (Competance) †¢Competancy is a process centric and not content centric # Learning Theories: 1. Classical Conditional Theory of Learning/Stimulus Response Learning 2. Response Stimulus Learning 3. Cognitive Learning 4. Social Learning 1. Classical Conditional Theory of Learning/Stimulus Response Learning: Russian Psychologist Evan Paulov conducted an experiment: Dog-Meat & Bell Meat called as the unconditional stimulus, unconditional stimulus creates unconditional response along with the meat he rings the bell. The bell called as neutral stimulus. . Response Stimulus Learning: – Trial & Error Learning – ABC Lear ning: A-Antecedent, B-Behaviour, C-Consequence – For every behaviour ‘B’, there is an antecedent ‘A’ to consequence ‘C’ any trial & error is accidental. 3. Cognitive Learning: – Meaningful mental map, which we create of a reality, which varies from person to person – Recognise repeated cognize 4. Social Learning: – Learning from society (e. g. peers, friends) – This is the highest form of learning followed by cognitive learning and then Stimulus response and there on †¢Dominant vs. Back-up style of learning †¢Trusteeship & ownership Leadership †¢Learning Style -Ignorance -Knowledge -Skills -Competency # Emotional Intelligence: -Empathetic Listening -Focus to the issue and not on person -Empowerment -Who is learning & what type -EI is experiential learning # Leadership: -Leadership is a â€Å"Style† -A good leader has a good ET – Emotional Intelligence # Steps to be a Good Leader: 1 . To be an empathetic listener 2. Tries to focus on the issues & solution path & not on the person 3. He empowers the followers 4. Brings in confidence building 5. To understand the learnig curve of the follower 6. He recognizes his own skills as well as others . He develops trusteeship (detachment) and not ownership (attachment) 8. He is known by his absence and not by his presence 9. He is a risk taker as he has a focus on locus of control 10. Leader is not a position, it is a process # Types of Leadership: 1. Autocratic 2. Democratic 3. Laissez Faire 4. Situational Leadership â€Å"Personality + People + Effectiveness = Leadership† â€Å"Situational Leaders has two styles – Dominant (own skill) & Back-up (learned skill)† -During critical situations, dominant style comes in place #Categories of Leadership: 1. Trasactional Leadership: Creates followers 2.Transformational Leadership: -24Ãâ€"7 approach, creates leaders, creates vision -Communicate it very clearl y to everybody -They act on the vision himself first. This develops inspiration among others and creates followers -People on their own join the leader -He creates future leaders -To develop EQ : – He has to take risk (emotional) which comes only through experience – He needs to be aggressive, go getter, pushes others & himself in achieveing goals †¢Emotional Intelligence is the separator between Manager & Leader # 6 Personality Traits: 1. Locus of Control: strong internals, control over situations 2.Machawallism: -High Mach (highly manipulative) -Low Mach (Less Mach) 3. Type ‘A’ & Type ‘B’: -A = Aggressive, go getter -B = Laid Back 4. Self Motivating: pause —? Listen –? Reflect –? Respond. -It starts with self-awareness of one’s thoughts, words & action. It converts a reaction to a response. A good leader will have a moderate level of self-monitoring 5. Risk Taking 6. Self-Esteem # Blate & Motoum Managerial Gr id (Training model) (1, 1) – Impoverished leader – least concern for result & people (9, 1) – High concern for results & least for people – Autocratic (1, 9) – Termed as ‘Country Club Manager’.High concern for people but less for result (9, 9) – Ideal, Proactive Manager – The leader. Equal concern for both. It’s not a destination but a journey which a leader constantly tries to achieve. He is a situational leader. He uses the people’s competencies toward’s achieving goals. He is always ‘Ethical’. Requires tremendous self-discipline. Role Personality is a connectivity between the Role & the Goal. They have personal sense of humility (5, 5) – ‘Middle of the Road Manager’. It is a process. Tries to rise from the strategic level to visionary level. # Personality: 1.Definition 2. Traits 3. MBTI/Thomas Profiling 4. 16 PF/FIROB/DISC 1. Definition: â€Å"It is a sum total of inner & outer attributes†, where – Inner Factors: Values, attitudes, perception, belief, paradigms Outer Factors: Physical disposition, mannerism, habits, behaviour. All the factors put together comprises of personality -Role Clarity is subjective whereas Goal Clarity is objective -Inner factor drives the outer factor -When meaningfulness of the goal is aligned with values, perception of role, the individual develops the role personality in line with the goal. In most cases he is effective in achieving goal. For e. g. : Student has a goal of learning a subject: i. He must have a clarity what he is learning ii. Learning, as we know is absorption of knowledge into doable action called skills. iii. This is of the purpose of acquiring knowledge is to transform an adopted behaviour then the learning is effective iv. The individual needs to focus this aspect of learning & align these aspects with consistently, he tends to play the Role Personality effectively v. Although all goals are measurable, the measurable may not indicate his learning (at times he may get higher %age, at times lower) vi.All in all his focus should be to absorb knowledge & change his behaviour. So long as this focus is maintained, we can see him maintain Role Personality quite effectively. This is seen through his behaviour of active participation in all situation to acquire and assimilate indulging & convert them into skill & behaviour changes †¢Scenario: A, B, C, D are team members in a certain vertical. – ‘A’ is hardworking but, stickler to time – he works strictly 9. 00am – 5. 00pm. His output is remarkable – ‘B’ – Intelligent, genius, erratic, maverick – available only when a crisis occurs.Arrogant & individualistic – ‘C’ – Quiet, laid-back, seemingly unintelligent, very obedient, slow worker, everyone likes him – ‘D’ – Into mood swings, creates goals, disappear for days & returns & works for long hours to complete his tasks, rarely talks, very helpful though, does not like to be asked questions The above 4 team members are assigned a project for SMG (self-managed groups) The time frame is 1 month. All 4 team members need to be optimally used. Design a goal & perform a DPA by mapping characteristics, personality Create roles & goals to attain effectiveness Strengths & weakness of each team member:Team Member ‘A’: S: Time management, hardworking, goal oriented, focused, commitment, disciplined, organized W: Rigid Team Member ‘B’: S: Crisis management, confident, go-getter attitude, individualistic W: Arrogant, selfish, individualistic (low people skills) Team Member ‘C’: S: Strong values, obedient, strong interpersonal skills, approachable, quiet, laid-back, good follower W: laid-back, slow coach, quiet Team Member ‘D’: S: Goal setter, Innovator, compassionate, helpful W: Disappe aring act, moody, does not like to be asked questions # Need Drive theory of Motivation: -All needs are basic requirements for organization When a need arises, it indicates a deficit -This deficit leads to a disturbance in comfort zone -There arises instantly within the organism, a type of drive that propels the organism to fulfill this deficit, thereby restoring comfort zone -When this fulfillment is complete, the organism is set to achieve total satisfaction -This drive is called motivation -This drive is automatic, instant, since it has its origins on survival of species, inshort it is instinct driven -Hence motivation is a term given to instinct driven that almost instantaneously develops the need deficit into need fulfillment -This is the animal side of the humanIn day-to-day scenarios, we need to identify the diference between needs & wants. Needs are basic, wants are desired NEED(instinct) + DESIRE = Want (Rational) Need when fulfilled gives 100% satisfaction (does not leave any memory). A need is always an instant gratification # Frustration Model: It is derived from need-drive theory of motivation. If a need deficit arises in an individual, it creates a drive almost instantly to fulfill this need. While in process of fulfilling the need, if there arises an obstruction or barrier, the organism will anyway be fulfilling it through alternate means.This altered behaviour is always unsound behaviour This behaviour is a repetitive behaviour. â€Å"Without action there is no motivation† # Fundamental Theories of Motivation: 1. Reinforcement Theory of Motivation 2. Goal Path Theory of Motivation The individual’s motivation is a result of 2 influences – Internal & external # What motivates you? -Content theories of Motivation: i. Maslow’s Theory of needs ii. Fedrick Hersberg’s – Two factor theory of needs iii. ERG Theory of Needs – albert iv. David Mc Cleeland’s Theory of Needs # Why and how are people mo tivated? – Process Theories of Motivation i. Stacey Adam’s Equity Theory i. Victor Vroom’s Theory of Expectancy iii. Poter Roller’s Theory of Intrinsic rewards 1. Reinforcement Theory of Motivation: It has 2 parts: a. Positive Reinforcement b. Negative Reinforcement Encouraging behaviour that are desired by an organization constitutes the frameqork of +ve reinforcement. The employees are encouraged to regret & certain behaviour that are desirable for the end customer of goal This is usually done by rewards, hence also termed as motivation by Rewards On the other hand there are certain behaviours which are not in line with organizational needs. These behaviours need to be discouraged.Instead of allowing these behaviours to repeat, organization resort to collapsing these behaviours. This is brought about through the process of punishment termed as motivation by punishment or –ve reinforcement. Historically such reinforcement is resorted to at the fun ctional level of organization, where rewards & punishment form the value criteria of employees’s behaviour As 1st time learners, all of us resort to stimulus response learning, our behaviour are also stimulus response based. Hence, it is natural for us to respond to the reinforcement method of motivation 2. Goal – Path theory of motivation:

Female genital Mutilation in Sudan Essay Example | Topics and Well Written Essays - 3500 words

Female genital Mutilation in Sudan - Essay Example Focus is also drawn on the different ways through which the government of Sudan, different international agencies, local non-governmental organizations, and civil groups are working to stop this oppressive practice. Communities that practice FGM perform it in varying ways. The World Health Organization has developed three major categories of FGM. There is Type 1, Type 2, and Type 3. Type 1 female circumcision is referred to as clitoridectomy. This mainly involves the removal of the tip of the prepuce, with or without excision of part or the entire clitoris. In Type 2, there is the removal of the clitoris together with part or all of the labia minora. Type 3 female circumcision is also called infibulation. This involves the removal of most or all of the female genitalia. In this type, there is also the stitching of the vaginal opening, where only a small opening is allowed for urine and menstrual flow (Islam & Uddin 2001, p. 72). Type 3 is considered the most severe form of FGM. In Su dan, there are different names that are used to refer to each of the three types of female circumcision. Type 1 is referred to as â€Å"Sunna.† This involves the removal of the tip of the prepuce. ... For instance, some of the Muslim Sudanese hold that female circumcision is supported by Islam. On the other hand, the Muslim theologians in Sudan believe that there is no provision for FGM in the Koran (Islam & Uddin 2001, p. 73). Nonetheless, Turshen (2000, p. 145) notes that FGM is linked to Islam, even though not all Muslim countries uphold it. With regard to the prevalence of female circumcision in Sudan, the findings of Sudan Demographic and Health Survey (SDHS) of 1989 -1990 show that 89% of the ever-married women have undergone some form of FGM. The Northern part of Sudan ranks high, with approximately 99% of the ever-married women having undergone circumcision (Landinfo 2008, p. 6). In 2001, Islam and Uddin conducted a study in Sudan to determine the prevalence of female circumcision in the region. Their study focused on Haj-Yousif and Shendi, which are in the North, as well as Juba, in the South. Nonetheless, in this paper, the focus is not on South Sudan. The study of Islam and Uddin (2001, p. 74) revealed that female circumcision is highly prevalent in Sudan. 100% of the respondents in Shendi, and 87% of respondents in Haj-Yousif had undergone circumcision. The most prevalent form of female circumcision was found to be the Pharaonic circumcision, which is the most severe form. In Sudan, the process of female circumcision is performed by lay practitioners. These have little or no knowledge on the female anatomy, or medicine. The conditions under which female circumcision takes place in Sudan are below the hygiene standards. Furthermore, no anaesthesia is performed on the females before circumcision, and there is no sterilizing of the instruments used to perform female circumcision (Landinfo 2008, p. 9). A major reason why

Professional, Ethical, and Legal Issues in Healthcare Essay

Professional, Ethical, and Legal Issues in Healthcare - Essay Example A nurse who is a friend to the mother of the family suffering from cancer finds herself in a difficult situation in trying to be loyal to the mother, to the two sons in the family and to her profession. Having been a good mother, she chooses not to disclose her medical condition to her sons so as to avoid negatively affecting them psychologically. The ethical dilemma that the nurse finds herself in by not disclosing this information will be put in focus. Introduction There are principles that form the foundation of the ethical codes guiding the professional practice in healthcare. These are the foundations of moral theory in healthcare profession with code of ethics that call for honesty, integrity and responsibility. As such, these ethical codes that have been developed for healthcare professionals provide guidance in their practice. These would normally be created in response to anticipated or actual ethical conflicts (Schweitzer 2010). They are usually difficult to comprehend and only make sense when applied in real life in cases of ethical ambiguity. The contents in these codes vary with the risk involved in a specific profession. For example, in psychology, the code of ethics would define in greater depth the relationship with the client due to the high degree of personal relationship a psychologist would have with the client. On the other hand, there would be minimal interaction between a laboratory technician and a patient; hence the relev ant code of ethics would be more on the need for accuracy and reliability in their tests. White defines bioethics as the application of the general principles of ethics in healthcare (2005). Indeed, all the areas in health care, including staff utilization, clients’ direct care and finance allocation are bound by ethics. Ethics would raise a question but would not provide an easy answer. Among the reasons that make ethics important in the modern world include advancement in technology, changing society and more knowledgeable clients. There are three main groups in healthcare affected by ethics, namely; the providers, patient and family. They would normally have different perspectives on how they would like issues handled. This becomes more complicated when bioethics, physician theories and societal stake are considered (Warren 2011). Just like other practitioners in healthcare, nurses uphold each principle in their routine practice. However, there are times when these principles conflict calling for the nurses’ ethical decision making in choosing which of th e principles becomes priority to be upheld at that moment. In such cases of ethical dilemma, there is no ‘right’ solution. Fant defines ethical dilemma as a problem that does not have a satisfactory resolution (2012). Thus, different ethical choices on an ethical dilemma could be made, but this does not justify any choice as being ‘wrong’ or ‘right.’ The definition of ethics varies from one nurse to another and would normally be shaped by experience, values and beliefs of an individual nurse. The code of ethics with respect to the

A comparison of Still Lifes by Paul Cezanne and Francisco de Zurbran Essay

A comparison of Still Lifes by Paul Cezanne and Francisco de Zurbran - Essay Example Most impressionist paintings were done out of doors, many depicting scenes from everyday life, often with several figures and using bright, vibrant colors, and without any emphasis upon exact details. This is more unusually is an indoor scene and a still life, but there are still the bright colors and the lack of exact detail. It is exactly what it was meant to be – an impression of a kitchen scene. The items are very casually laid out, on what appears to be a kitchen table, almost with the appearance of being thrown down, and the background looks as if the artist has used it to clean his brushes, including as it does tiny amounts of many different colors, yet at the same time the viewer is able to distinguish exactly just what is being depicted as clearly as in the much more formal and realistic work earlier work by Zurbà ¡ran. Impressionism was not abstract art.

FAMILIES IN CGLOBAL CONTEXT Research Proposal Example | Topics and Well Written Essays - 2500 words

FAMILIES IN CGLOBAL CONTEXT - Research Proposal Example In other words, families have become more pluralistic in recent times then ever before. Changes because of globalization mean the decline in the American families. Charles Murray, a reporter in Wall Street Journal directed illegitimate births as the most critical problem with more devastating affects than any crimes. American families have to confront challenges like high divorce rates, illegitimate births, pre-marital sex, decline in birth rates, loss of family functions, etc. The highest official divorce rates are in United States when compared to other developed nations. The high divorce rates are a threat to the continuation of familial institution. Children experience mental illness, perform poorly at their schools or display other signals of maladjustment. The sexual revolution is also the dominating factor that threatens the existence of American families because it promotes premarital sex and illegitimate births. Transformation in American society had been escorted with decli ne in fertility. Before the era of globalization, families were considered to be miniature society (Roopnarine, 2005). The shifting of functions from the family to other institutions has made it less important because of decrease in social responsibilities. With the advent of globalization, families in Mexico that were once customarily closely knit, appear to be dispersed, specifically among the young rural migrants who go to urban areas for better job opportunities. Meanwhile, the elders of the family are abandoned frequently to fend for themselves while the young male members of the family are lost in the intermediary regions of the urban centers (Grusky, 2001). The migrations of young people have made them abandon their cultural values for which they were known for. Also, there has been a decline in equally positive close relationship and bond that existed between the elders and the youngsters of

Marketing Strategies Assignment Example | Topics and Well Written Essays - 1750 words

Marketing Strategies - Assignment Example It will shape the product features based on cost considerations. The marketing plan will allocate resources where they will gain the best return. Packaging, advertising, and distribution will all be a part of the marketing plan. To begin writing an effective marketing plan first requires a detailed marketing strategy based on a number of strategic criteria. Market power is the degree of penetration that a company or product currently has in the market. If a company has a large market share, or market dominance, they can benefit from the ability to set prices and less competition. If a company has a small market share they will be forced to follow the pricing plan of the market leaders. Market dominance can also be attained if there are barriers to entry for other companies. Dominance can also be acquired if the product has a sufficient profit margin to allow pricing competition. If a product has low market share, easy entry to the market, and a low profit margin the marketing will be from the aspect of low market power. This will be a consideration when placing the product in the market. The product may opt to challenge the market leader or find a niche market. The company may also place the product as a market follower or suitable substitute for the market leader. Innovation strategies determine the extent that a company or product will lead or f... Continual innovation and product improvement is mandatory. Other products may not be as influenced by innovation and consumers may prefer proven reliability rather than innovation. Innovation strategies also extend to the distribution and customer base of the product or company. New uses for an existing product is innovation. Finding new outlets, markets, and generating new customers is also an innovative strategy. Growth Strategies One of the most basic measurements of a firm's success is its growth rate. Aside from selling more of an existing product, a company may decide to grow vertically or horizontally. The company that employs vertical integration seeks to control the raw material, production, transportation, and marketing of their product ("Vertical Integration"). In this strategy, the firm profits from every step in the product's life. Horizontal integration is the acquisition of additional processes or markets that are similar to the existing base. An oil company that acquires additional refinery capability through purchase or mergers is employing horizontal integration. Products can be marketed to targeted and segmented markets with this strategy. A firm can likewise grow through either diversification or specialization. Kraft Food has benefited by offering a wide range of food products. A firm can also benefit from specializing in a product and becoming the market maker for the item. Kleenex and Xerox were both known for their focused product and expertise. Aggressiveness Strategies Part of the business plan will be plans for future expansion. The strategy will determine how fast and in what ways the firm will grow. These factors will be determined by the ability to take risks, financial leverage, level of bureaucracy, and aggressiveness. A company is

Impressions of Visiting Vatican Museum Essay Example | Topics and Well Written Essays - 750 words

Impressions of Visiting Vatican Museum - Essay Example Before going into the particular sensations that my senses felt, it is necessary to begin to describe the experience with relation to the mood that I had upon arriving at the Vatican museum. The mood itself was a mixture of feelings that helped to add to the overall experience and the level to which I can recall it. Firstly, I was exhausted from my travels. Secondly, I was fatigued from standing in line under the hot Italian sun for over an hour. Thirdly, I was thrilled to realize the fact that finally, I was going to be able to realize my dream. And lastly, upon entering the museum itself, I was in pure amazement. What greeted my senses was something that is difficult to retell while keeping the experience as powerful as it was to me. Upon entering the museum, I remember the distinct smells that I encountered. It was an interesting medley that recalled the smell of an air conditioner that had just been turned on for the first time of the season mixed with the powdery smell that ston e buildings often have. What was noticeably remarkable was the fact that the museum did not smell like a museum. Instead, it smelled more sterile. This had the combined effect of somewhat distancing the exhibits from the reach of the visitor. Had the location smelled more like a museum, it is likely that I would have in some way met at least a few of my prior expectations regarding the exhibits housed within. One factor that detracted from the overall experience was the sheer number of people that were in the Vatican museum at the same time that I took my tour. Although I expected that such a tourist attraction would be crowded, I had no way of preparing myself for the number of people that I encountered. Unfortunately, at times, the crush of the crowd did take away from the overall experience as I felt that at certain times I was being herded through the museum without having the necessary time to take in the setting and/or the artwork that greeted me.  

EXAM Essay Example | Topics and Well Written Essays - 1250 words

EXAM - Essay Example Hence, when one is faced with a situation that one cannot explain, tension rises. This tension leads to pain. The pain arises from the views of Western psychology that everything must be accounted for within this lifetime. Buddhism argues that all the problems we experience are due to ignorance, which can be overcome by practicing Dharma. Quality of life depends on inner development of peace and happiness. Unlike Western Psychology that relates one’s problems with external factors that condition behavior, Buddhism argues that to avoid pain, we must first achieve peace in our minds. Guided by spiritual values, one is able to achieve inner peace. Western Psychology on the other hand does not recognize spiritualism or spiritual values as ways of avoiding pain. Western Psychology seeks to use facts that can be hypothetically tested to arrive at generalizations. Since spiritualism cannot be scientifically tested, Western Psychology does not recognize it in explaining the sources of one’s pain. Buddhism assumes that imprints are carried over from past life. Western psychology on the other hand assumes that everything must be accounted for within this lifetime. Western psychology links what it cannot explain to the unconscious. Although Buddhism can embrace many assumptions of Western psychology, it would use conditioning and imprints from previous life to explain why one experiences pain. Buddhism teaches how to examine the mind and explains the causes of pain and misery; and the causes of happiness. It teaches how to cultivate a mind of virtue that leads to enlightment. Buddhism argues that transforming the mind to view suffering as natural and helpful helps to maintain balance in the body. It argues that suffering should be viewed as part of a greater path which makes the mind pure and reaches a state where one conquers suffering. Thinking of suffering as an unnatural occurrence leads to

Pfizer Essay Example for Free

Pfizer Essay Pfizer has new technology that helps to access the system easily. They have a smart card consisting of proximity device so that as a person walks near a computer, there is a signal emitted by smart card which verifies you. There is use of pin number so that no one can use another persons card and pin number is used in other parts of the company such as making charges at cafeteria and accessing the building physically. When Pfizer is deploying information system, they take their time to cooperate with people who do business in order to know the risks involved in storing and transferring information. They do not under protect information or overprotect it. Business can be impeded by overprotecting information which can make security be thrown out. They partner with information technology and business in order to protect business, offer quality products and services and make profit. (Betancourt, 2002 pp19-21). Describing policies and measures used by Pfizer to ensure confidentiality, availability and reliability of data and information Confidentiality of data is ensured through a system that employs cryptography such as public key and symmetric key in order to encrypt and decrypt information and data. There is an entity that reads sensitive information and data and the key represents a secret property. To ensure availability of data and information Pfizer has prescription coverage to ensure access to its medicines that are new and widely prescribed. Through number 866 706 2400, there are live operators to guide patients according to their needs and the programs for public assistance according to medical needs and income. The reported outcome of patient’s measures determines how treatment of a disease affects patients. To ensure there are results that are useful clinically data gathered must use reliable cognitive psychology, clinician and patient input. This is done by determining the purpose of patient reported outcome in order to demonstrate its reliability. (Nurss, 1998 pp11-12). How Pfizer organization protect loss of data In order to avoid loss of data, Pfizer protects privacy of information collected from external organizations through online opportunity process of submission which supplements privacy policy of Pfizer which can also apply to personal data and identifiable information. For Pfizer to ensure personal data is secure, it uses data customary that protects electronic and manual processing. Security technology in online opportunity ensures securities that avoid loss of data, misuse of data, unauthorized disclosure, destruction and alteration of data. Steps taken to ensure data remain accessible in event of catastrophic event such as fire and other natural disaster Actions are taken to lower exposure to risk arising from hazard to safeguard development efforts. Developing systems for early warning helps in reducing risks and having capabilities to respond to catastrophic events. Disaster recovery is used in recovering information in event of catastrophe. Disaster recovery planning is devoted to prepare for action to respond to catastrophic event. Assessment in disaster recovery is simulating catastrophic event and planning for disaster recovery in order to have recovery need that are specified. Plan for disaster recovery state duration the recovery should take and the state of data expected by the users and management need to be informed all the time of these specifications which are substantiate by recovery assessment. Things I think Pfizer could do to further enhance information security  There should be enough circulating space inside the organization so that staff can move around freely without use of lifts. Employees should avoid calling their colleagues using phones but instead use face to face communication about information concerning the organization and cellular office space should help to make communication easy. Government should take action to develop mechanisms for sharing information with private sector by engaging private sector actively in determining requirement of information and having a partnership that is based on trust. ( Parker, 1996 pp21-23).

Glaxo Smith Kline Pakistan Limited Commerce Essay

Glaxo Smith Kline Pakistan Limited Commerce Essay GSK Pakistan Limited was created on January 1st 2000 through the merger of SmithKline Beecham Pakistan and Glaxo Wellcome Pakistan and it stands as the largest pharmaceutical company in Pakistan today. GSK leads the industry in value, volume and prescription market shares. Some of their key brands include Augmentin, Panadol, Seretide, Betnovate, Zantac and Calpol in medicine and renowned consumer healthcare brands include Horlicks, Aquafresh, Macleans and ENO. GlaxoSmithKline (GSK) is one of the Pakistans largest research-based pharmaceutical corporations that discovers, develops, manufactures and markets branded human health products. GSK has two main business divisions, pharmaceuticals and consumer healthcare. This profile deals with the pharmaceuticals division, which generates 85% of GSKs sales. GlaxoSmithKline (GSK) is also Pakistans leading research-based pharmaceutical company with a powerful combination of skills and resources that provides a platform for delivering strong growth in todays rapidly changing healthcare environment. GSK also has leadership in four major therapeutic areas anti-invectives, central nervous system (CNS), respiratory and gastro-intestinal/metabolic. Company produce medicines that treat six major disease areas asthma, virus control, infections, mental health, diabetes and digestive conditions. In addition, GSK is a leader in the important area of vaccines and are developing new treatments for cancer and has a growing portfolio of oncology products. The company also has a Consumer Healthcare portfolio comprising over-the-counter (OTC) medicines, oral care products and nutritional healthcare drinks, all of which are among the market leaders. GSK is primarily focused on the development, production and distribution of its own products. GSK is an important contributor to the national skills pool in areas of chemical and pharmaceutical research, manufacturing, management practice and sales marketing. FACTORY LOCATIONS: Registered Office: 1. GlaxoSmithKline Pakistan Limited 35-Dockyard, West Wharf, Karachi -74000. Telephones: 92-21-2315478-82 Fax: 92-21-2313632 Other Offices: 1. GlaxoSmithKline Pakistan Limited F-268, S.I.T.E., Near Labour Square, Karachi-75700 Telephones: 92-21-2570665-69 Fax: 92-21-2572613 2. GlaxoSmithKline Pakistan Limited 18.5 km, Ferozepur Road, P.O. Box No. 244, Lahore Telephones: 5811931-35 Fax: 5820821 GSKS FINANCIAL DATA: Five Years Sales YEARS SALES (rupees in billions) 2002 6.9 2003 8.1 2004 8.8 2005 9.4 (Growth by 6.2%) 2006 10.1 (Growth by 7.1%) GRAPHICAL REPRESENTATION OF SALES (in millions) Companys Five Years Profit YEARS PROFIT (rupees in billions) 2002 0.54 2003 1.02 2004 1.47 2005 1.81 (Growth by 23.3%) 2006 1.66 (Decrease by 8.2%) GRAPHICAL REPRESENTATION OF PROFIT (in millions) Revenue breakup Benchmarking Ratio Name WYETH SEARLE ABBOTT GSK Current Ratio 4.10 1.714 4.76 4.4 Inventory Turnover 1.69 times 10.11 times 4.69 times 3.0 times Total Asset Turnover 60% 10.2% 1.17 times 1.1 times Profit Margin on Sales 0.182 0.032 0.17 0.16 Earnings Per Share 112 3.53 10.21 12.2 Return on Assets 10.9 3.2 19.9 21.5 CORE VALUE OF GSK GSKs value is based on its research strength linked to production marketing. The core of value creation is from the inventories of new chemical entities and it captures value through a high intensive sales and marketing process. Essential to the overall value proposition is the synergy of RD, production and commercial activities. GSK has been committed to its social and health related activities. Good Corporate Citizen is core value of GSK. Core values of GSKs can be summed up as a belief in performance with integrity, coupled with entrepreneurial spirit, focus on innovation, a sense of urgency and a passion for achievement. GSK are working to ensure the culture guides and informs everything they do by adhering to these core principles, they seek to create a climate in which the best people can always achieve to their full potential, and in turn help millions of people live longer, healthier and happier lives. NEW CHEMICAL INVENTROIES Production and commercial activities Synergy of RD GSK High intensive sales . Core Competencies of GSK : GSK has the core competencies in genetics, to enable them to integrate genetics effectively and responsibly into their current practice. Competency in these areas represents the minimum knowledge, skills, and attitudes necessary for health professionals from all disciplines (medicine, nursing, allied health, public health, dentistry, psychology, social work, etc.) to provide patient care that involves awareness of genetic issues and concerns. BUSINESS PROFILE GlaxoSmithKline (GSK) is one of the Pakistans largest research-based pharmaceutical companies that that discovers, develops, manufactures and markets human health products. It is an innovative company that produces branded products only, which it has developed itself. The company has two main divisions, pharmaceuticals and consumer healthcare. The consumer healthcare businesses of GSK consist of over-the-counter (OTC) medicines, oral care products, such as the toothpaste brands Aqua fresh, MacLeans and Sensodyne, and nutritional healthcare drinks. The pharmaceuticals division is the largest part of GSKs businesses and can be divided into prescription drugs and vaccines. The headquarters of GSK are located in the UK. The company operates in some 160 national markets. GSK conducts RD at more than 20 sites and employs 15,000 employees in RD. GSK is involved in many different RD partnerships with academic institutions, biotechnology companies and other pharmaceutical companies. The compa ny has a leading position in genetics and in new drug discovery technologies. BUSINESS PROFILE Pharmaceuticals Consumer healthcare Vaccines Prescription drugs Over-the-counter (OTC) medicines Oral care products Nutritional healthcare drinks Viral Vaccination Toothpaste Bacterial Macleans Aqua fresh Heart disease Infection Skin condition Sensodyne BUSINESS STRATEGY: GSKs business goal is to be a world leader in pharmaceutical industry. In order to achieve this, the company seeks to improve its RD pipeline, using a focused drug portfolio strategy and selective in-licensing agreements for the external contracting of RD. The company links RD closely to commercial operations to maximize the value of its RD portfolio. Furthermore, GSK seeks to increase brand name recognition among customers and to develop improved versions of older products, on which new patents can be obtained. It is a common strategy of branded drug producers to develop improved versions or more convenient formulations of drugs on which the patents have expired, and to persuade doctors and patients to use the enhanced version. Business strategy Being best place for best people to do their best work Optimising the performance of key products Delivering the product pipeline for patients Improving access to medicines Supply Chain of GSK Supply Chain Management according to GSK, is a process for ensuring continuity of supply through the rapid identification of actual and potential supply chain issues enabling pro-active management and the prevention of low and out of stock situations. SUPPLY CHAIN MISSION OF GSK: GSKs Supply Chain mission is to construct, harmonize and improve quality of all the product and go with the intend of satisfying the chain of suppliers suppliers and customers customers by providing right product, at the right time, in the right quantity, to the right place and becoming highly recognized by our employees, customers and shareholders and abiding by Government laws and regulations GSKs Objective of Supply Chain Issue Management à ¢Ã¢â€š ¬Ã‚ ¢ To prevent low and out of stock situations occurring. à ¢Ã¢â€š ¬Ã‚ ¢ Pro-actively identify any potential supply chain issues with the purpose of preventing low stocks and stock outs occurring. à ¢Ã¢â€š ¬Ã‚ ¢ Resolve supply chain issues, at a local level where possible, excepting issue types categorized for immediate escalation. à ¢Ã¢â€š ¬Ã‚ ¢ Provide a fast and effective mechanism for escalation where issues cannot be resolved at local level. à ¢Ã¢â€š ¬Ã‚ ¢ Enable delivery of root cause analysis complete with follow up action to ensure the causes of actual and potential low stocks and stock outs are understood. à ¢Ã¢â€š ¬Ã‚ ¢ To have one information source for all supply chain issues. à ¢Ã¢â€š ¬Ã‚ ¢ To have global visibility of all supply chain issues. à ¢Ã¢â€š ¬Ã‚ ¢ To enable rapid tactical response to commercial opportunities Supply Chain Integration P R O D U C T F L O W sales force activity (SFA) Transportation Supplier factory Warehouse Manufacturing Sales stations/Warehouse Customer Pharmacies Distributors I N F O R M A T I O N F L O W GSKs Supply Chain Structure Mr. Ahmad Jamal Qudsi (Commercial) Distribution Manager DISTRIBUTION MANAGER MASTER SCHEDULER MASTER SCHEDULER CAPAPCITY PLANNER PRODUCTION PLANNER PRODUCTION PLANNER Mr. Sajjad Zahid Shaikh (GMS) Manager Procurement, Shipping, Contracts, Regulatory affairs. PROCUREMENT MANAGER Exports mANAGER Local/ IMPORTED PURCHASE mANAGER Warehouse mANAGER Mr. Obaid (GMS) Purchase Manager b-65 F-268 w.w LHR Sales Force Activity ( Demand Generated)Supply Chain Process Manufacturing Planning (Demand Generated) Procurement Planning Vendors (Quotations asked) LC Follow up import dispatches Clearance Transit Time Material in Warehouse Material Available For Production Production Released by LTR FO Batches Packing line FO Quarantine Central Depots Dispatches Institutions Lab Test Results (LTR) Satellite Depots Distribution Wholesalers Retailers GSKs Global Manufacturing Supply Procedure GMS site disposals will be co-ordinated within a consistent process alongside communication plans. A consistent process will enable GMS in meeting the business case objectives. The process proposed will generally recommend decisions to the CET based on a balance between: à ¢Ã¢â€š ¬Ã‚ ¢ Realising the synergy benefits from transferring production à ¢Ã¢â€š ¬Ã‚ ¢ Maximising sale proceeds à ¢Ã¢â€š ¬Ã‚ ¢ Minimising local labour redundancy à ¢Ã¢â€š ¬Ã‚ ¢ Ongoing supply security à ¢Ã¢â€š ¬Ã‚ ¢ Managing political and other local sensitivities Key features of the site disposal process are: à ¢Ã¢â€š ¬Ã‚ ¢ It is GMS-managed with involvement of key stakeholders at the sites and in Legal Entities à ¢Ã¢â€š ¬Ã‚ ¢ External contracted assistance will enable global marketing of the sites A phased and co-ordinated approach: Phase 1 preparation Phase 2 search Phase 3 negotiation The Escalation Process Step 1:Daily (regular) The regular dialogue between Demand and Supply managers is the foundation of SCIM. SCIM is only invoked when the agreed supply plan cannot be achieved and a resolution cannot be found by the demand and supply managers. Low stock and out of stock events are entered into the SOLS system or generated automatically. Demand and Supply Managers discuss entered events as appropriate. Supply Managers make proposals to resolve the event. Demand managers read proposals and agree by accepting the suppliers response to events with the customer satisfaction flag as a default value of yes or disagree and move the flag to no. If no is selected then commentary may be entered into the escalation field. This enables a report to be run selecting any items marked for escalation. Demand and Supply Mangers proactively view trends, and any issues which might potentially impact the supply of product. Step 2: Wednesday The Supply Manager prepares for the PCM. Reports are available from SOLS and other supporting computer systems identifying all issues. In particular, the SCIM report from the Data Warehouse. This is to be run for All Issues (in SOLS issues are referred to as events). The Supply Manager cuts his report in preparation for the PCM at the latest this is done on the Thursday morning. Step 3: Thursday The PCM is held. At sites of supply the PCM review all Low Stocks, Out of Stocks and any issues and their potential impact on the sites ability to supply. Where no resolution to actual and potential issues is found then the Supply Manager invokes the escalation procedure with the ALM or equivalent. N.B. Issues can be escalated by either the Demand Manager or the Supply Manager Step 4 Thursday/Friday The ALM (or equivalent) is brought in by either the Demand or Supply Manager to help resolve the issue identified. The ALM (or equivalent) runs the SCIM report from the Data Warehouse filtering on Unresolved Issues. If resolution can still not be made then the ALM progresses the issue with the Regional Logistics Director (RLD). RLD chair conference call with ALMs (or equivalent) and any guest Demand or Supply Managers required. RLD compiles consolidated market view for region of issues. RLD tries to find network solutions to supply issues. RLD flags unresolved issues as critical issues in SOLS. Step 5 Monday The Area Logistics Managers / Directors are brought into the discussions to assist resolution if necessary especially where a potential stock rationing situation might occur. VP of Global Logistics (VPGL) runs the SCIM report from the Data Warehouse filtering on Critical Issues. VPGL chairs conference call with RLDs and any guest ALMs, Demand or Supply Managers required. VP compiles consolidated market impact for issues. VPGL flags any unresolved critical issues as exceptional in SOLS. VPGL makes decision escalate critical issues and engage commercial and manufacturing executives. Step 6 Tuesday Formal review by RSDs, Vice-President Global Logistics, Senior Vice President Global Logistics and Strategy and any other appropriate senior manager. The SCIM report is run from the Data Warehouse filtering on Exceptional Issues. An output from this meeting (or teleconference) can be the establishment of a virtual team to resolve the issue. It will exist until the issue is resolved and is lead by the ALM (or equivalent) supported by the RLD. Where stock rationing is required the RLD will trigger the Rationing process VPGL reports on the commercial impact of exceptional issues. The RLD assumes overall responsibility for resolution of the exceptional issue. Supply Chain Process: Supply Chain Issue Management (SCIM) is a process for ensuring continuity of supply through the rapid identification of actual and potential supply chain issues enabling pro-active management and the prevention of low and out of stock situations and regular communication occurs between demand and supply managers. The process is driven from bottom up rather than top down. Issues are to be resolved at the lowest level. Trending analysis is to be done by the Supply Managers. The process is two way between demand and supply. Both supply performance and forecast accuracy are to be reviewed. SCORE MODEL P L A N N I N G BUYING USING STORE SELLING RM Manufacturer Make Deliver Source Make Deliver Make Source Deliver Source Deliver Source Plan Indenters GSK, Pakistan Distributors Return Return Return Return Return Return Supplier Suppliers Supplier Company Customer Whole salers Customers Customer PLANNING: Planning in GSK, Pakistan, is done by the demand function unit of the finance department. Below is a general diagram which shows how the planning takes place: The Process: The process starts with the doctors which prescribes medicines to the patients. The patients then ask for the drugs from the chemist which is basically a retailer. From retailer an order is then passed on to the distributor which then simultaneously ask for the drugs from the company. Now the daily data on sales is sent to the SMART Department of GSK which uploads the information in the database. Finally the queries and reports which are generated by the SMART Software help the Demand Managers, in the finance department, to predict the future demand for the specific drug. SMART Software basically creates the trend which help managers see the rise and fall in a drugs demands over the years. This helps them to accurately tell the procurement managers the demand required for the raw materials to be purchased for a specific drug. BUSINESS PLANNING: The corporate executive team of GSK does strategic planning on every last day of week which is co-ordinate within a consistent process alongside communication plans. The process proposed will generally recommend decisions to the CET based on a balance between realizing the synergy benefits from transferring production, Maximizing sale proceeds, Ongoing supply security. Corporate executive team (CET) Meeting Finance Department Discuss CET VP, Planning Sourcing Negotiation CET approval Corporate executive team . DEMAND FORCAST: As mentioned above the demand in GSK is forecasted by the Demand Function Unit of Finance Department. Finance department provides 24 months rolling aggregate demand forecast, which is known as ADS (Approved Demand Statement). This statement shows individual demands for all product lines demanded by end users. The softwares used by the finance department to predicts demands are BIPEX (also known as BPCS) and JD-Edwards. On the demand side markets review their sales plans on a regular basis (at least monthly depending on size of market) and feed into the supply sites Production control Meetings through the Supply Managers UNPLANNED DEMAND Unplanned demand is a demand, which comes unexpectedly Like at the time of War, NATURAL DISASTERS OR ANY EPIDEMICS According to GSK, they have a policy to maintain four weeks safety stock to handle the uncertainties. Stock, in the three categories, intended to maintain supply continuity resulting from a significant event that is unplanned. Top 20 Products (as defined by GSK annual sales, Pharma/Consumer Healthcare) Medically Critical and Access to Medicines products New Chemical Entities (NCEs), including Product Line Extensions (PLEs) SUPPLY STRUCTURE: Supply Issues (potential and actual) are reviewed formally each week. At the supply sites this is done at the weekly Production Control Meeting. Supply Issues are managed on a daily basis but the formal weekly meeting brings all aspects of supply and demand together for review; it adds a framework. Then after the supply plan has been made it is forwarded it to the Procurement Department. Master Production Schedule The entire production is based on this plan weather it is Tablet, syrup, or injectables manufacturing. This is set up on the bases of forecasted and some times unplanned demand as well. Date for all the batches is set up according to this plan but when there is a sense of urgency then there are some changes made. The figure below shows this process is generated: Master Production Arrival This is the inventory, which is going to arrive in bulk, and it is the job of Master Production Scheduler to arrange the bulk. This bulk can either be for export or for the market demand done through forecast. He also sets up when to make the required batch on which date. STOCK MANAGEMENT: GSK used inventory management system First in First out (FIFO). Inventory management (FIFO) of strategic stock to ensure proper rotation and reduce the potential of data used. Items at stock keeping unit level where, based on the forward sales forecast/ sales orders, the level of inventory is predicted to fall below 50% of the agreed safety stock within the next 90 days. SAFETY STOCK: GSK stores stock in ware houses for maximum flexibility of supply purpose. The stock is taken into account within 1 month of time. Material Management Planning: GSK, Pakistan is using BIPEX (also known as BPCS) to effectively and efficiently handle the Material issues. All transactions are made electronically into BPCS known as Business Planning Control System. If there is an additional requirement due to abnormal demand then there are some changes made in MRP. Capacity Planning Capacity means a measured ability to accomplish work. Capacity planning is a process in which capacity is planned based upon expected demand and it needs to be balanced with required capacity utilization and it also outlines the capacity requirements for the production, availability of machines and what are the standard hours, which they are required to meet the forecasted demand. And to manage the capacity control process GSK Pakistan is using 2 systems known as JD-Edwards and BIPEX which is also called as Business Process Control System (BPCS). SUPPLY CHAIN CONFIGURATION: Supply chain manager act upon the process enabling pro-active management of potential and actual supply issues in order that the impact on lost sales is minimized. Supply chain manager resolve supply chain issues, at a local level. The Supply Manager prepares for the PCM. Reports are available from SOLS and other supporting computer systems identifying all issues. In particular, the SCIM report from the Data Warehouse. . MAKE OR BUY DECISION: GSK Pakistan is currently importing 72 drugs, which includes all its vaccines and expensive oncology medicines such as Hycamtin. The reason why GSK imports these products are because there manufacturing is very expensive and Pakistan is not self sufficient in the raw materials which are required to make these products. Infact the climate of Pakistan makes it very hard for GSK to manufacture vaccines here. Thus all its vaccines are imported from Belgium. Also, these products cater to a very small market segment and manufacturing them here would not be profitable. SOURCING: Gsk Medicines contain active ingredients. They also contain other, additional ingredients called Excipients that help ensure the stability, safety and effectiveness of the medicine. They are also added to improve the medicines taste and appearance and to make it easier to take. Some may be used to prolong the life of the medicine Pharmaceutical ingredients include both synthetic chemical substances as well as material with biological orgin. Various control methods with chemical, microscopic and microbiological testing is covered during the course. In addition, the different national and international quality control regulations for pharmaceutical ingredients are taught. SOURCING PROCESS The Weekly Process At the day-to-day level the Demand and Supply Managers are engaged in managing the fulfillment of the order book, ensuring forecasts are kept up to date, handling any un-forecasted (abnormal) demand, and resolving any issues. This is normal daily activity. Any issues arising must be discussed with the objective of resolving at local level. Issues can come from either the Demand or the Supply side. The Stock Out and Low Stock (SOLS) Data Warehouse system is the main vehicle for recording and reporting issues and actions taken between Demand and Supply Managers. It is used as a formal means of identifying and tracking issues and the actions taken to resolve them. It is a dialogue application for use by the Demand and Supply Managers. Demand nodes will accept the proposals or escalate through the hierarchy. Data can be manually entered into SOLS. Supply sites must respond to recorded stock-out and low stock events according to SCIM time table PROCUREMENT GSK has an extremely large procurement organization largely left over from the 2001 merger between Glaxo Welcome and SmithKline Beecham. The purchasing group set a goal of developing what it called best value purchasing strategies, ensuring that GSK is getting the best possible price and cost for everything it buys. That means negotiating the best prices and making sure those contracts are adhered to. GSK has two types of purchases i.e. local purchases and foreign purchases PURCHASES LOCAL PURCHASES FOREIGN PURCHASES Raw Packing Material Group purchases Non Group purchases (party purchases) ) NIP (non inventory purchases) PROCESS FLOW FOR PURCHASE PR incorporated in:Incorporated By:Against Requisition of:BIPEXPPICPurchasesJD EdwardsConcern dept.NIPPurchase of inventory is approved through Firm Plan Order (FPO) by Purchase Planning and Inventory Control Dept (PPIC) and incorporates in system N.I.P. Concern department generate approved Purchase Receipt. Procurement Department (P.D.) received signed copy of FPO by PPIC and PR for N.I.P. Type of PurchasePURCHASE FLOW OF PRODUCT A FOREIGN PURCHJASES LOCAL PURCHASES Purchases Raw Material Packing Material N.I.P. Fixed Assets Consumable items Quotation calling Selection of Supplier through Quotation Evaluation Form Placement of Purchase Order (PO) by P.D. Information in PO: Supplier name Delivery schedule Quantity Required Rate (as decided with supplier) A SUPPLY of GOODS: Nature of MaterialMaterial Supplied at:PurchasesStores.NIPConcern Dept. 3way check: Invoice WITH P.R. P.O. by Commercial Finance Issuance of INVOICE by Supplier. Information in invoice: Delivery Challan #. P.O.# Recording of Liability depends on LTR. DOCUMENTS ISSUED BY DEPT.AFTER RECEIPT of MATERIAL from SUPPLIER Supply of:Documents IssuedBYTOPurchasesReceivers Ticket.(RT) Delivery Challan.Stores Dept.Quality Control (QC) Dept.NIPMaterial Receipt Note (MRN)Concern Dept.Incorporated in System. Lab Test Report (LTR) Incorporation of approved lots in BIPEX by QC Up to the Quality Accounts Dept. runs an auto report identify NEW LTRs Entries made by Accounts Dept. for new LTRs: DebitCreditENTRY for NEW LTRStock (@Standard rate)xxxPurchases Price Variance (PPV)-GSTxxx PPV- Other than GSTxxx Provision for purchases(actual payable amount)xxx PPV variance (with the Diff.) Fav/ (Un-Fav)xxxxxxPurchases (actual payable amount)xxx Purchases ContraxxxENTRY for NEW INVOICE (after approval of QC)Provision for Purchasesxxx Vendor Control A/Cxxx B Entries made by Accounts Dept. for new MRN: DebitCreditENTRY for NEW MRNExpense A/C (NIP)xxx NIP Commitment A/C xxx ENTRY for NEW INVOICE NIP Commitment A/C xxx Vendor Control A/Cxxx Payment to VENDOR Entries made by Accounts Dept. at Payment Stage DebitCreditVendor Control A/Cxxx Bankxxx Tax Liabilityxxx Raw Material Packing Material Purchase FROM Quotation Calling 3RD PARTY Selection of Supplier Raw Material Finished Goods GROUP Prices are already decided between GlaxoSmithKline Pakistan Limited Group Companies. Placement of Purchase Order (PO) by PD they incorporates PO, in BIPEX. Receives PERFORMA INVOICE (an agreement to sell) by Supplier. Type of L/C Opening of Letter of Credit (L/C) with Bank. Information in L/C: L/C #. Mode of transportation. Type of L/C. (Usance / Sight) Receipt of Shipment Schedule (SS), Suppliers Invoice Bill of Lading [B/L] (Negotiable Non-Negotiable Copy). Information in SS: Date of Shipment. Type of freight paid. At usage at sight C Submission of Negotiable Copy of B/L to Shipping Co. Submission of Non- Negotiable Copy of B/L to Ministry of Health for Approval of Material (as required under Drugs Act). Delivery Order (Delivery Challan) receives from Shipping Co. Submission to Custom for Clearance of Shipment. Receipt of SHIPMENT Certificate of Approval for Material by Ministry of Health alongwith exemption certificate (if any). LTR Up to the Quality Receipt of Agents Bill Testing of Shipment by QC Materials Average Lead Time GSK Pakistan only uses air freight to acquire imported materials and its lead time is approximately 120 days. Note that when materials arrive they also take clearance time which is about 4-5 days for air freight

Mainstreaming and Inclusion of Exceptional Children? Essay -- essays p

Mainstreaming and Inclusion of Exceptional Children? In an ever-changing world, the context of education continues to grow. The demand for higher, more diverse education often leaves teachers battling to acquire skills for improved classroom performance. It is crucial to recognize that the need for higher education is implied for all students, including those with special needs. â€Å" The term mainstreaming was first used in the 1970’s and describes classrooms where students with disabilities and students who do not have disabilities are together (Mainstreaming in Classrooms, 2002. p. 1)†. Within special education the question of mainstreaming often arises as a solution for superior learning. Mainstream and inclusion programs have proven beneficial to all students, teachers and communities as a whole. The Individuals with Disabilities Education Act was reformed in 1997 and calls for free and appropriate education for special needs students. The IDEA emphasizes a least restrictive environment, in which children with special needs are educated to the highest of their ability (). For many special needs children the highest level of appropriate education lies within mainstreaming. Participation in mainstream programs depends heavily upon the academic ability and social skills of each individual child. The Individual Education Plan is used to monitor the ability, progress and future goals of each student. â€Å" Not only must the IEP contain a statement of how the child’s disability will affect participation in the general curriculum, but it must explain why any student will not be participating in the general classroom...â€Å" (Moore, Gilbreath, Maiuri, 1998, P.3). There are many levels of special education, including ma... ...sabilities in General Education Classrooms: A Summary of the Research. Retrieved October 30, 2002, from Http://interact.uoregon.edu/wrrc/AKInclusion.html Rush, M., Timmons, D., Holtsman, M., Medlock, L.(2002, April 15). Inclusion...Yours, Mine, Ours. Retrived October 31, 2002, from http://rushservices.com/Inclusion/hompage.htm Mainstreaming in Classrooms.(2002, May). Retrieved October 30, 2002, from http://kidshealth.org/PageManager.jsp dn=KidsHealth&lic=1&ps=307&cat_id=20184&article_set=22988 McNamara, B., McNamara, F.(1995). Mainstreaming. Retrieved November 2, 2002, from http://www.parentsoup.com/edcentral/vocabulary/bsa070.html Should Special Needs Children be â€Å"Mainstreamed† or Sent to Seperate Classes? Retrieved October 31,2002, from http://www.parentsoup.com/offline/special/articles/0,8248,191748_170012,00.html

Affirmative Action - Public Opinion vs. Policy :: Affirmative Action Racism Discrimination Essays

Affirmative Action - Public Opinion vs. Policy When Justin Ketcham, a white college student from the suburbs, thinks about affirmative action, he thinks about what happened when he sent out letters seeking scholarships so he could attend Stanford University after being accepted during his senior year of high school.The organizations that wrote back told him their money was reserved for women or minorities. To Americans like Ketcham, it's a matter of fairness. The average white male will claim that it's not fair to attempt to rebalance scales by balancing them the other way. Students like Ketcham are also more likely to claim that affirmative action is a program geared towards curtailing workplace prejudices that really don't exist anymore.But when Hillary Williams, a black insurance company manager from the inner-city, thinks about affirmative action, she thinks about the time she had to train three consecutive white male bosses for a job that no one even approached her about filling. To her, it's also a question of fairness. African-Americans like Hillary feel that there is just no other was besides affirmative action to level the playing field in certain businesses.And so the disparity in public opinion begins. A racially-divided America creates separate groups, which "Affirmative Action issue taps a fundamental cleavage in American Society" (Gamson and Modigliani 170)--each with their own view of affirmative action on different sides of the line. Government attempts to create policy based upon the voice of the people but affirmative action seems to present an almost un-solvable dilemma. Traditionally, it had been a policy that was greatly scrutinized for its quotas and alleged unfairness towards Blacks, but at the same time it had also been praised for its inherent ability to help minorities gets jobs they deserve but could not obtain otherwise. So how do we reach a "happy medium" so-to-speak? In American political culture, it appears as though individualism and egalitarianism are values that find themselves on opposite ends of the political battlefield. In a complex world of political ideology and political culture are sets of values and principles that are widely endorsed by politicians, educators, the media and other opinion leaders that make up the definition of what is to be American (Feldman and Zaller). Some favor the values of individual freedom, especially individual economic freedom, over other values, especially equality and popular sovereignty (egalitarianism). These people are labeled Conservatives. The other side of the spectrum consider themselves as Liberals (Feldman and Zaller).Because we live in a meritocracy created by the strong forces of capitalism, there is a tendency for people to fall behind either in the economy or in the academic community.

propaganda techniques :: essays research papers

Name Calling: giving an idea a bad label, a negative term that sticks. Glittering Generally: opposite of name-calling, uses â€Å"good† words and phrases that have a positive â€Å"glittering† appeal. They are broad, vague, and often meaningless emotionally charged words. Transfer: uses symbols usually, to carry over the authority, sanction and prestige of something respected and revered over to something else in order to make the latter acceptable. Usually patriotism, religion, religion, and associating yourself with someone popular /famous and using that person’s â€Å"coat tails†. In above picture, featuring John Kerry and John Edwards, I see some transfer with the flag behind them. It seems to symbolize that they are still strong and honorable just like the flag. I think they are hoping to seem patriotic to our country despite all the nasty things they said about our president. Testimonial: having some famous, respected person say an idea (or person) is good (or bad). In the photo of Bush and Schwarzenegger, I think Bush is trying to use Arnold’s popularity and fame to get him a few votes not only in California but also around the nation. Plain Folks: Speaker tries to convince his audience that he and his ideas are good because they are of the people, the â€Å"Plain Folks†. Trying to make us think that he/she is just like us. In picture to the right, bush is seen conversating with the troops like one of the boys. Card stacking: involves arranging facts and arguments to be very one-sided. Usually involves leaving out significant information. In the above picture, this person is trying to force these kids into believing they should follow what he says. He is using force and not telling the entire story. Band Wagon: Everybody is following this program, so follow the crowd,† jump on the band wagon†. In picture to the right, it suggests that everyone should smoke marijuana because even the chipmunk is. The Big Lie: if something is repeated enough times, people begin to accept it as truth.

Me at the Age of 30

Me at the age of 30 My vision for the future involves many goals that I know I will have to work hard to achieve. I feel that the way to achieve my goals will still be difficult. My professional goals in life are to find a job that makes me happy,have a family and a child . Firstly I want to assure a stable and well paid job. I hope I will be working in medicine or pharmacy. I think in this field there will always be a job open for me.Hospitals are always in need of doctors to help with people that get sick, or hurt in an accident or anything else. Also all the people need drugs when they get sick,so in my opinion pharmacist is a great job for a girl . In this field I will get benefits for my family, such as health insurance. To get a job like this takes many years of work, study and practice. A job who I also dreamed since I was little is flight attendant.I started to think a lot of this option and I really like it because I enjoy speaking English and others foreign languages. I ima gine I will be flying over oceans and countries. Secondly I’m going to start a family. By getting married and having a family I believe will bring joy into my life. I want to make sure my own family is happy. I really don’t see myself with lots of children at the of 30, but I expect I will find a soul mate.It is beautiful to watch your children grow up before your eyes and this is what I want, but not at the age of 30. I believe, as well as most people, that you are successful in life if you have raised a family. I wish I’ll become a serious person who knows what she wants. Also I want to live in a beautiful city like Timisoara ,Iasi,Brasov or Pitesti. I’ll have a big apartment and a nice car. Becouse I live in a small village ,I know how hard is to be a commuter so I want my future to be in a big city. So that’s how I see myself at the age of 30.

Policies to Reduce Pollution

The two policies that are mostly used to reduce pollution are the taxation of the pollution producers (Pigovian tax) and standards-change approaches. The Pigovian taxes are usually generally levied as an excise tax, which will raise the price of the goods produced. This causes the company to produce less which in turn lowers pollution. The standards-charge approach is to tax the pollution directly. The government determines the level of pollution that it thinks is appropriate, and then will charge a fine for each unit that is above the appropriate amount. This is how the standard-charge approach rewards the companies that produce less pollution and punishes the companies that exceed the allotted pollution amount. Unfortunately, standard-charge approaches don’t enable policy makers to control the air quality. The government has to estimate how much a company will reduce their pollution when they are fined. If the government sets a fine to low, the company may determine that it is cheaper to pay the fines rather than reduce its pollution. This also will not give the company an incentive to reduce their pollution level below what the government has set as the desired limit. The positive benefits to these measures are that our ecosystems are healthier and this also helps the health of the people living in the local environment. Air pollution is known to cause a great deal of disease in the population, especially respiratory disease. The environments ecosystems will benefit when people and companies lower their use of fossil fuels, this will help to lower greenhouse gases. Taxes and fines always have some sort of losses involved, both to the companies and to the government applying the fines. When the different taxes are levied, companies will find ways to reduce costs by either cuts in staffing or outsourcing what they are able to send to foreign companies. Another cost involves the failure of the government. The different taxes and fines levied on companies are paid over to the government and the government is notorious in their inefficiency in the use of their funds. Most government agencies are overly bureaucratic and cumbersome which can create unnecessary regulations that are impossible to enforce. It is impossible to determine the exact level of pollution reduction needed to produce a healthier living environment. At this point in time, society controls the pollution levels until the costs outweigh the benefits of additional controls. This assumption isn’t always valid. It has been proven, through past actions, which as air quality improves it becomes more difficult to reduce the levels of pollution at a reasonable cost. Even though society demands a clean environment for health reasons, it is a higher concern depending on income levels. The higher the income level the more of a concern it will be. Those with a lower income that are without medical insurance are less inclined to worry about pollutions that will harm them over time. Pollution should be reduced so that it will not negatively affect the health of the population or the environment. Unfortunately we also have to weigh the lowering of pollution against the cost of job loss and the cost of goods. In the end, as long as the government policies are able to reduce pollution to a level that is socially acceptable they can be viewed a success.

Why Did the South Lose the Civil War

Why did the South Lose the Civil War? Beginning as a battle of army versus army, the war became a conflict of society against society. In this kind of war, the ability to mobilize economic resources, the effectiveness of political leadership, and a society’s willingness to keep up the fight despite setbacks, are as crucial to the outcome as success or failure on the battlefields. Unfortunately for the Southern planters, by the spring of 1865, the South was exhausted, and on April 9, Lee surrendered to Grant at Appomattox Court House, effectively ending the war.Economically, the war was a benefit for the North and a disaster for the South. The North began the war with several advantages. The North held a distinct lead in nearly every resource needed for warfare. Not only was the population deficit of the South compared to the North, roughly around 13 million, but the statistics for factories, goods produced, railroad tracks, textiles, and firearms all succeeded the south by mor e than half. As a result, the union army became the best-supplied and fed army while southern armies suffered shortages of food, and clothing.Shortly after the start of the war, Lincoln would further suffocate the south economically by implementing the Anaconda Plan, a naval blockade. Industrially the South couldn't keep up in output but also and in manpower. By the end of the war, the South had, more or less, plenty of weaponry still, but it just didn't have enough men to use the guns. Let alone enough men to defend the perimeter around the confederacy to protect its territory.Another key aspect that the North held over the South was the determination of Abraham Lincoln to win, and the incredible staying power of the people of the North, who stuck by Lincoln and stuck by the war in spite of the first two years of almost unrelenting defeat. A problem of the South was that it lacked the moral center that the North had in this conflict, the idea of Union, was important. One of the Sou th’s objectives’s for creating their own government, was to give states more power than the central government. This was ironic, because a strong central government was what the South needed, but what Abraham Lincoln had in the North.Abraham Lincoln also offered a better explanation to his own people of what they were fighting for. He displayed this leadership through his progressive steps towards emancipation, one early example being the contrabands of war. The army and congress determined that they would not return escaped slaves who went to Union lines and classified them as contraband. They used many as laborers to support Union efforts and soon began to pay them wages. This would seem exceedingly important as the war turned into one against slavery.Despite the lack of economic and political power, the South was also at a loss of collective will. Certainly the course of the war, the military events, had a lot to do with the loss of will. The Southerners hoped that they would win spectacular victories on Northern soil, and that they would be able to exhaust the will of the Northern people, and they failed to do so. The battle of Gettysburg with the largest number of casualties is often described as the war’s turning point. The Union defeated attacks lead by Confederate General Robert E. Lee, ending Lee's invasion of the North.With regard to military turning points, the outcome of the war also became inevitable in November 1864 with the reelection of Lincoln and the utter determination to see the things through, and the finding of leader U. S. Grant, the man to provide the leadership that the North needed. As long as Lincoln was determined to prosecute the war and as long as the North was behind him, inevitably superior manpower and resources would win it out. With more men, more money, more industrial power, and a strong unity for the will to win, the Northern Union crushed the Southern planter aristocracy and it never regained its poli tical power again.

Analyse How an Adaptation of Your Choice Deals with Gender †Catwoman Essay

The representation of female super heroes in the media can be said to have had huge institutional, political and social influences that would suggest those in power are favoured at the expense of those without. Female super heroes tend to promote sexualisation and stereotypical gender roles of women, throughout comic books and super hero movies, but why? In this essay I will look at the character of Catwoman, and her representation as a female, particularly in the 2004 adaptation film â€Å"Catwoman†. Originally, she is an iconic character in the batman series. Created in 1940 by Bob Kane (batman creator) and Bill Finger, she has had a strong presence in batman comics and adaptations since then. Her role as a mysterious burglar and jewel thief led her to just miss out on a place in the top ten, ranking 11th in IGN’s ‘Top 100 comic book Villains of all time’ (2009) and 51st in Wizard magazines ‘100 greatest villains of all time’ list (2006). The character has been used in hundreds of comic books, as well as video games, radio stations, TV series, animated series and films. Although she is featured in mostly batman productions and texts, Catwoman was given her first comic book series in 1993, written mostly by Jim Balent. Several years down the line, Catwoman stared as the lead role in the feature film, made in 2004. The movie was an example of post feminism at its best, as in the 1970’s, only 15% of action adventure movies cast female leads. The movie was directed by Pitof and was released on July 23 by Warner Bros. and Village Roadshow Pictures. The cast members include Halle Berry, who plays Catwoman, Benjamin Bratt, Sharon Stone and Frances Conroy. I have chosen to analyse this movie because females are not usually given dominant roles in superhero movies, especially as the lead character. There are many stereotypes that surround women, and I believe this movie challenges those. The film was inspired by the DC comics villain of the same name, however stars a new character, Patience Phillips. There are several similarities to the original character. For example, she has similar office job and is killed by someone she works for. In the 1992 movie staring Michelle Pfeiffer, she uncovers a dark secret in the company and is thrown to her death from a great height. The plot for the more recent movie is very like its predecessor. In both versions she is brought back to life by a group of wild cats. However the most relevant similarity is her appearance and costume. Throughout the film, Catwoman is dressed in a tight black latex costume, black connoting mystery and evil. This material is often associated with sexuality; it clings to her body and shows off her curves. Over the years her costumes have become even more provocative, with this Catwoman being more fetish than ever. These clothes represent Catwoman as a sexual image to be looked at by the opposite sex. Laura Mulvey describes this as the Male Gaze. She explains â€Å"In their traditional exhibitionist role, women are simultaneously looked at and displayed with their appearance, coded for strong visual and erotic impact so it can be said to connote to-be-looked-at-ness. † (1975, p33). It is arguable that woman in the genre of action, drama and super hero are not represented as women, rather an object of sexual desire. The women featured in such genres are slim, pretty, and all wear tight clothing. Lillian Robinson refers to woman super heroes as a pin up girl in a cape, rather than genuine characters (2006). The skimpy outfit has great erotic significance (Richard Reynolds 1994) and could create a negative portrayal of females, as well as being a very bad influence for the young women and girls who watch the movie, or read the comics. Clearly, the media heavily influences teenagers already. They follow the latest fashion trends from celebrities, coolest haircuts, and they diet and loose weight to look like the people they see on TV and in magazines. They look up to the people in the media, and the image of Halle Berry in the cat suit, may encourage young girls to objectify themselves in a similar way. Already, Playboy as a brand has become a fashionable thing, for young girls even at the age of 8. They have the playboy bunny pencil cases, posters and duvet covers. Just like this, cat woman may encourage youthful girls to dress inappropriately with increased sexuality. Even Catwoman’s make-up connotes sexualisation. Her lips are painted scarlet red, which draws your attention straight to her mouth, as well as being the colour of lust to stimulate sexual arousal. This idea is due to the fact men and women have more blood flowing through their lips whilst aroused, turning them a darker shade. Halle Berry was most likely cast because of her beauty. Her eyes, lips, body and sex appeal come before everything else in the movie, (Roger Ebert, 2006). The director of this movie has chosen to portray her as an object of sexual desire for men, rather than a role model for the power and liberation of women. Typical of Hollywood movies, the overtly sexualised view of women is rooted in the darkest chamber of male desire, (Kevin Maher, 2005). She appears powerful and dominant, however, she is in fact the opposite, and inferior to the gaze of men. Laura Mulvey says in her book Visual Pleasure and Narrative Cinema, â€Å"Women as image, men as bearer of the look†, (1975). Personally this idea is predictable and brings nothing new to the genre. Wonder Woman first appeared on screen wearing a gold bra and blue knickers, and in those 36 years gone by, you have to ask yourself, why do superheroes need to be dressed so provocatively? Why can’t the action hero fight crime and ‘kick ass’ in a baggy jumper and a pair of dungarees? Kevin Maher, 2005). I believe the reason behind this is due to the fact that the representation of characters such as Catwoman and Wonder Woman where created by those with power over women. The institution DC comics created both in the 1940’s, which was largely if not entirely controlled by men. Women had no control over their creation and as powerful as Catwoman may be, she is still just an image of the male gaze. Created in a time where females had no authority, they where not able to argue against what could be considered as an unfair representation. Angelia McRobbie has a theory in defence of this sexualised representation, and believes men did not create this image. Women have gained the equality they where fighting for, and now they are using their assets to their advantages. In this case, Catwoman is willingly showing of her body to attract the male gaze, because it gives her power over men. She summarises that post feminism positively draws on and invokes feminism, (1994). However it’s not all negative, Over time things have changed, the presence of female leads in the super hero genre has increased, and to an extent therefore, time has favoured the female lead. Some 50 years ago, males where seen as the hero, there to protect the fragile women. Superman and Lois Lane are a classic example of where the lead role is given to a man, he is strong and courageous, while Lois is inferior to him, she has no special abilities and relies on him completely. However, the number of women in this genre proves a success for the feminist woman and an improvement in today’s society. Iconic actresses such as Angelina Jolie and Uma Thurman have stared as the female lead in modern action movies. Lara Croft, Tomb Raider and Kill Bill are both examples of woman taking active roles, and how accepting it is in this particular genre. Jolie also stared in Mr and Mrs Smith, which showed her as an equal to her husband, just as strong and just as capable of fulfilling the dominant lead. Catwoman has evolved over time, first known as The Cat in DC comics; she then progressed onto TV screens. Her sexual appearance made her an object of desire to the eyes of the male audience, and a role model to girls who wanted to be her, Suzan Colon (2004). In the Halle Berry adaptation, Catwoman is reborn a new woman, sleek, sexy, ambitious and not held back by the restraints of society. She is rebellious and follows her own desires as a feline crime fighter. This representation of Catwoman forces the question that perhaps contemporary women are constrained by the rules of society and are not free. Catwoman challenges the female stereotype and adopts the masculine lead role in this superhero movie. She is a protagonist, independent and capable of standing alone. A crucial scene in the movie shows Catwoman arguing with a large masculine looking man. She demands he turn down his music, which results in her physically attacking him. The argument ends with him lying on the floor with her foot on top of him. This scene portrays her as superior to the man, and the physical pose makes him vulnerable to her. This scene is important, because when she was her human self, known as Patience, the man would not listen to her. As Catwoman, her voice is heard. Simone de Beauvior Invokes ‘the independent women’ who wants to be active, wants to take things for themselves and refuses the passivity men try and want to impose on her. The modern woman accepts masculine values; she prides herself on thinking, getting a job and working to pay her own way, existing on the same terms as man, (1949). Catwoman does exactly that. She completely demolishes feminine stereotypes at the end of the movie when she rejects the love interest and chooses to be a free independent woman. She is not reliant on anyone, especially a man and because of that, I believe this movie demonstrates a victory for women. â€Å"Freedom is power† (Catwoman, 2004). Motivated by revenge, no man stands in her way. However another scene tells a very different story and shows off Catwoman as purely a vision of sexual desire. As she is transformed from patience Phillips, into Catwoman, supposedly now free and independent, we are reminded of her physical qualities. ‘Reminded’ is an understatement actually; it’s thrown in our faces. As she walks across a rooftop the camera angle starts from her feet, moves up her legs and to the top of her body. Paying particular attention to her bum, first impressions are everything! This scene completely confirms Mulvey’s theory, and as Liz Wells suggests, certain films objectify the female star, (2004). However Catwoman is not the only dominant female in this movie. Hedare Beauty is the company Patience works for, and is run by a man named George, or so you are made to believe. Yet in fact, the one calling all the shots is his wife, Laurel. She is controlling the strings of her puppet husband and forces him to her way of thinking. She is an evil, sinister character, full of greed, and in the end she kills her husband in cold blood. She is the villain in this movie, but also a woman in power and free from the constraints of society. In the early 1970’s, after the second wave of feminism, more women were gaining better professions and breaking out of the stereotypical roles. The post modern figure of a female became more appealing to both genders, and resulted in women wanting to achieve higher status in the world of work. An example of such acceptance was seen in the recently released song by male pop artist Ne-Yo, called ‘Miss Independent’. This continues the suggestion of the need for change in the way female super heroes where represented in order to capture the post-modern audience. Catwoman and Laurel Hedare are both great examples of female presence in superhero movies and the result of female empowerment. Judith Butler brings an interesting theory to the table. She believes gender is free floating, rather than fixed, that males and females aren’t simply masculine and feminine. She says that gender is a performance, rather than an aspect of our identity and we behave differently on different occasions. This theory suggests Catwoman isn’t necessarily challenging gender roles by taking on the masculine super hero, but rather an act she’s choosing to play. Women can be masculine because the individual chooses their gender identity. â€Å"When the constructed status of gender is theorized as radically independent of sex, gender itself becomes a free floating artifice, with the consequence that man and masculine might just as easily signify a female body as a male one, and woman and feminine a male body as easily as a female one† (Judith Butler, 1990, p6). Interestingly she suggests that if there where no longer conventional roles for either gender it would be considered the norm for a woman to be in a position of power at work or for a man to stay at home looking after the children. After looking into the history of Catwoman, her creation, and other adaptations in the past, I believe her image is over sexualised. The film is centralised around a beautiful woman, wearing the sexy, tight black costume to do none other than attract male attention. They do however promote that she is a powerful woman and has the freedom to do as she pleases. The fact that a female is the lead role in a movie of this genre is a positive thing. Although the message left behind is that to have freedom and power, you have to entail being objectified. In the end, this movie has done the same as its predecessors, portray woman in a sexualised, unrealistic and in a possibly insulting way.